Insulin Conversion & Supply Calculators

Convert insulin doses between units, millilitres (mL) and milligrams, match a dose to the right syringe, and plan how long a vial or pen will last. This hub also converts blood glucose between mg/dL and mmol/L and translates A1c into estimated average glucose. Every tool is educational and built on insulin product labeling and the ADA Standards of Care.

Educational use only. These conversion and supply tools use standard published formulas. Always verify with your pharmacist, doctor, or diabetes care team — and confirm the concentration printed on your own insulin before drawing a dose.

🔄 Insulin Unit & Volume Conversion Tools

Move accurately between units, mL and mg across U-40, U-100, U-200, U-300 and U-500 concentrations, and find the matching syringe marking.

📊 Blood Glucose & A1c Conversion Tools

Convert glucose readings between mg/dL and mmol/L, and translate A1c into estimated average glucose (eAG) and back.

📦 Supply, Refill & Prescription Planning

Estimate how long your insulin will last, how many vials or pens you need, and when to refill — useful for travel and pharmacy planning.

How insulin unit and concentration conversion works

Insulin is dosed in units of biological activity, but it is drawn and stored as a liquid volume. The bridge between the two is the concentration printed on the label — the "U-number" — which tells you how many units sit in each millilitre. Once you know the concentration, the conversion is simple arithmetic.

Core conversion formulas

Volume (mL) = Units ÷ Concentration
Units = Volume (mL) × Concentration

Example: 30 units of U-100 insulin = 30 ÷ 100 = 0.30 mL. The same 0.30 mL of U-500 insulin would hold 0.30 × 500 = 150 units — which is why concentration always has to match the syringe.

Common insulin concentrations

StrengthUnits per mL1 unit equalsTypical use
U-4040 units/mL0.025 mLSome veterinary insulins
U-100100 units/mL0.01 mLStandard human insulin (most products)
U-200200 units/mL0.005 mLConcentrated pens (e.g. lispro U-200, degludec U-200)
U-300300 units/mL0.0033 mLGlargine U-300 (Toujeo)
U-500500 units/mL0.002 mLSevere insulin resistance (Humulin R U-500)

Safety first: a U-100 syringe is calibrated for 100 units/mL only. Using it with a different concentration — or drawing U-500 into a U-100 syringe — is a well-known cause of fivefold dosing errors. Concentrated insulins are designed to be given with their own pen or a matching syringe.

Estimating how long your insulin will last

Supply planning answers two everyday questions: how many days will this vial or pen cover? and how many do I need for a 30- or 90-day prescription? Both come from the total units in the container and your average units per day.

Days supply formula

Days Supply = Total Units in Container ÷ Units Used per Day

A 10 mL U-100 vial holds 1,000 units; a 3 mL U-100 pen holds 300 units. At 40 units/day, a vial lasts 1,000 ÷ 40 = 25 days. Remember the 28-day rule: most opened vials and pens should be discarded after about 28 days even if insulin remains, so refill planning should use whichever comes first.

Frequently Asked Questions

Divide the number of units by the insulin's concentration. For standard U-100 insulin, mL = units ÷ 100, so 1 unit = 0.01 mL and 25 units = 0.25 mL. For U-40 divide by 40, for U-200 by 200, and for U-500 by 500. Always draw the dose with a syringe matched to that concentration.

The number is the concentration in units per millilitre. U-100 contains 100 units/mL and is the most common strength. U-500 (Humulin R U-500) is five times more concentrated at 500 units/mL and is reserved for severe insulin resistance. Because the same volume holds five times the dose, U-500 requires a dedicated U-500 syringe or pen — never a standard U-100 syringe.

A standard 3 mL U-100 insulin pen holds 300 units, and a 10 mL U-100 vial holds 1,000 units. More concentrated insulins hold more units in the same volume — a 3 mL U-200 pen contains 600 units, for example.

Divide the total units in the container by your average units per day. A 1,000-unit U-100 vial used at 40 units/day lasts about 25 days. Most opened vials and pens should also be discarded after 28 days regardless of remaining insulin, so use the shorter of the two figures for refill planning.

Divide mg/dL by 18 to get mmol/L, and multiply mmol/L by 18 to get mg/dL. For example, 180 mg/dL ÷ 18 = 10 mmol/L. mg/dL is used in the US, while mmol/L is standard in the UK, Canada, Australia and most of Europe.

No. Drawing U-500 insulin into a U-100 syringe causes serious dosing errors because the marks assume 100 units/mL. U-500 must be given with a dedicated U-500 syringe or the U-500 KwikPen, which are calibrated for 500 units/mL. Confirm any concentration change with your prescriber or pharmacist.

Sources

  1. American Diabetes Association. Standards of Care in Diabetes — 2024. Section 6 (Glycemic Goals) and Section 9 (Pharmacologic Approaches to Glycemic Treatment).
  2. U.S. FDA prescribing information for Humulin R U-500, Toujeo (insulin glargine U-300), and concentrated U-200 insulin pens.
  3. Nathan DM et al. "Translating the A1C assay into estimated average glucose values (ADAG study)." Diabetes Care. 2008;31:1473–1478.

Last reviewed: June 2025 · Conversions verified against insulin product labeling and ADA Standards of Care 2024